This case study showcases the development of the telemedical diabetes monitoring system GlucoTel™ as a learning case for RRI in ICT. It therefore links the activities along the development process with RRI aspects, such as stakeholder engagement or open access. By taking a business perspective, the study shows that the integration of RRI principles into company processes not only benefits patients, caregivers and other users but can also have benefits for the company, such as competitive advantage. In addition, the case study takes a global perspective and outlines the potential of telemedicine for coping with the global societal challenge of diabetes and secondary diseases which are a major health care problem worldwide.